The degradation behavior of magnesium-based alloys is obviously important for medical applications of biomaterials. Magnesium alloys were investigated as implant materials. This article critically summarizes the in vivo knowledge and experience that has been reported on the use of magnesium and its alloys to advance the field of biodegradable metals. The efficiency of the development approach is discussed. Thermo-physical and physical properties of liquid and solid phases during solidification are critical data for simulations. However, the number of alloys for which such information is available is limited, primarily due to the difficulty in experimentally determining these properties during the casting/solidification process. This article will focus on demonstrate the value of integrating the modelling of solidification and the associated. This include show changes in the composition of an magnesium alloys within its specification range can substantially affect its properties during solidification and how properties of the liquid can vary significantly in the mushy zone.