This article is focused on the analysis of tool wear in milling of Inconel 718. Inconel 718 is tough and highly temperature resistive material, which is used due to its excellent properties especially in aggressive corrosive environment. Machining of this alloy is still complicated. The feasibility of three inserts tested for milling of Inconel 718 has been shown in this work. Different cutting speeds and feeds were used. Experimental tests were performed in order to analyze wear evolution. It was found that cutting conditions and type of insert strongly affects tool wear mode. Surface roughness was studied as well as cutting force as a function of tool wear.