The objective of this work is to compare the performance of uncoated micro-end-mills and their effect on micro-milling of the Ti6Al4V titanium alloy that had been manufactured in the technology of Additive Manufacturing (AM). In this work, two different geometries of square-end micro-mills with two and fourcutting fluteshave been used. The effective tool geometry at the real micro-machining is rather problematic, because most of the tools are just down-scaled dimensions of standard cutters, so the cutting geometries might not be working well for all dimensions. The Ti6Al4V titanium alloy was made in technologyof Direct Metal Laser Sintering (DMLS). Micro-milling tests were done with use of high precision 5-axis KuglerTM micro-milling centre under dry cutting conditions. The performances were evaluated in terms of surface topography, burrs formation, surface integrity and tool wear.