Synthetic hydroxyapatite is used in biomedical engineering for its desirable mechanical properties. But not all scaffolds are biocompatible in use. The safety of implants depends on the competence of medical personnel, manufacturing technology, as well as biological, mechanical and other properties. Although there are regulatory standards for the safety of biomaterials, the assessment of their biocompatibility is a difficult task, which is associated with the properties of spacesuits, the duration of contact with tissues. The article proposes a method for assessing the safety of implants depending on various factors that form their biocompatibility.